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Xiao Yao San, a traditional Chinese medicine, was reported to exert therapeutic effects by increasing the expression of GPX4 and other ferroptosis-related molecules in the hippocampus of depressed rats (97)

Pentameric nCRP and CRP peptides 7782, 174185, and 201206 can control the inflammatory response resolving inflammation by reducing inflammatory cell endothelial adhesion and tissue migration, and the described CRP-mediated enhanced monocyte chemotaxis could be explained by local generation of mCRP (190, 191)

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Ferroptotic cells release DAMPs (e.g., HMGB1, ATP) and oxidized lipids, which activate pro-inflammatory immune cells

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