igf-1 lr3 risks hypoglycemia organ growth Insulin-Like Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer Frontiers | Insulin-like growth factor-1
Description
These compounds are formed continuously as byproducts of aerobic metabolism, through reactions with drugs and environmental toxins, or when the level of antioxidants is diminished, all creating the condition of oxidative stress

Gastroenterology 20 (No.23), 72607276

10.1016/j.bbrc.2013.10.115 79 LasuncinM

Additional complexity arises from IGF-1 stimulated signalling exerting differential effects in the mammary gland depending on whether it is pre-pubertal or pubertal, with switching between the activation of PI3K/Akt and Ras/Raf/MAPK signalling pathways (Tian et al., 2012)

2021;39:509528.e20
