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16, 2004 BioWorld Science Endocrine/metabolic

Jordt LM, Gellert M, Zelms F, Bekeschus S, Lillig CH

Their ability to target multiple pathwaysfrom initiating apoptosis and detoxifying carcinogens to reprogramming epigenetics and the tumor microenvironmentpositions ITCs as attractive candidates for integrative oncology approaches (113)
The pentose phosphate pathway (PPP) branching off glycolysis offers an alternate path for glucose degradation by producing nicotinamide adenine dinucleotide phosphate (NADPH) and ribose-5-phosphate for nucleic acid biosynthesis (Guo et al

Structural basis for molecular recognition of folic acid by folate receptors