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A pathogenic role for er stress-induced autophagy and er chaperone grp78/biP in T lymphocyte systemic lupus erythematosus

This has two effects: First, ethanol and acetaldehyde are inefficiently metabolized, and, second, electrons passing through the mitochondrial electron transport chain are diverted into forming harmful ROS, mainly superoxide (Hoek et al

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2.5 Neutrophil differentiation by DMSO treatment The differentiation of PLB-985 and PLB-985-KO cells into the neutrophil-like phenotype was performed as reported [22, 23]