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Previously, the poor outcomes of acral melanoma were explained by delays in diagnoses, but several recent studies have shown that acral melanoma has a high rate of locoregional metastasis and poorer survival outcomes than nonacral melanoma, even after controlling for melanoma stage

When side effects do occur, they are typically mild and dose-dependent

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5 Despite the lack of long-term safety data and the presence of unidentified impurities (4.1%-5.9%) in commercially available products, the majority of respondents (93%) indicated that they planned to continue using melanotan, stating that it increased their self-perceived attractiveness and overall quality of life