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When the Hippo pathway is inactivate, the abolition of YAP phosphorylation by MST1/2 enables YAP to translocate into the nucleus, subsequently interacting with the transcription factor TEAD to mediate the target genes expression such as RUNXs, SMAD, PPARG

Gene expression and Western blot analysis Total RNA was prepared from cells or tissue and reverse-transcribed

Reconstitute: Prepare the 100 mg vial to a final volume of 3.0 mL for a concentration of 33.33 mg/mL

Neutrophil apoptosis: relevance to the innate immune response and inflammatory disease