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acknowledges the University of Rhode Island for internship funding

The NM signal area was considerably smaller in patients with PD for 25 years compared to those with early PD (Fabbri et al., 2017)

Substitution of Met 123 with cysteine in CnrX abolishes Ni(II)-responsive expression and decreases the Co(II)-affinity by ~2000-fold [120]

While numerous synthetic ARIs have demonstrated excellent inhibition and shown promising results in animal studies, their efficacy in clinical trials was not very encouraging with some ARIs exhibiting adverse side effects

The median nerve runs through the carpal tunnel in the wrist, a narrow space surrounded by bones and ligaments