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Feldmesser M, Kress Y, Novikoff P, et al
Graying, on the other hand, is usually caused by the natural aging process or oxidative damage

doi: 10.1248/bpb.32.651

Although NOX2 has been shown to enhance the pathogenesis in IAV infection through endosomal NOX2 oxidase-dependent ROS production, NOX4 oxidase exerts a protective effect against IAV infection 72

Cheng I, Yang J, Tseng C, Wu J, Shariff-Marco S, Park SL, Conroy SM, Inamdar PP, Fruin S, Larson T, et al