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MT promotes MFN2-mediated WNT/-catenin signal Numerous studies have emphasized -catenins role in maintaining mitochondrial homeostasis in metabolic diseases and mitigating mitochondrial toxicity in neurodegenerative disorders through activation of the WNT signaling pathway [29]

Adverse effect profile of the herbal antidepressant St Johns wort (Hypericum perforatum L.)

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Glucocorticoids, for example, regulate the expression of glucocorticoid-sensitive genes by binding to glucocorticoid (GR) or mineralocorticoid receptors (MR) and subsequent activation of transcription through glucocorticoid/mineralocorticoid response elements ( GREs / MREs ) in gene regulatory regions 21,22

Representative images of NAMs are shown in Figure 1