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ranks 47th worldwide for maternal mortality, and is the only industrialized nation with a rising maternal mortality rate Sixty percent of hypertension-related maternal deaths are potentially preventable, which highlights missed opportunities for appropriate, recommended care of maternal hypertension There are several ways to improve outcomes for women affected by preeclampsia, including: Screening for risk factors and early hypertension control, nutrition, and exercise, which may help decrease rates of preeclampsia Providing easy-to-understand preeclampsia signs and symptoms education tools to improve patient understanding of these, and to discuss with their healthcare providers Supporting prenatal quality collaboratives that help hospitals to implement care practices that reduce early delivery and reduce severe pregnancy complications Providing access to midwives, doulas, and other trained childbirth attendants throughout the prenatal, labor, and delivery, and postpartum periods

The effect of homocysitaconate in this process is inhibition of the the MARS enzyme