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Practically, any before & after changes attributed to MIC/B12 should be viewed as adjunctive to fundamentalscalorie deficit, adequate protein, resistance training, daily steps, and sleeprather than a guaranteed pharmacologic effect

The theory is that cycling prevents receptor desensitization and reduces cumulative side effect burden

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12 Deficiency

As I said before PA is still thought to be the primary culprit here, other causes of B12 deficiency such as malabsorption caused by metformin, H2 blockers, PPIs, parasites, etc