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The cobalamin-induced changes in microbial composition and activity described above likely contributed to increased IL12/23p40 subunit levels in the colon

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In laboratory and pre-clinical settings, DSIP has been studied as a uniquely multifunctional endogenous regulatory neuropeptide across sleep, stress, neuroendocrine, neuroprotection, and geroprotective research applications: Sleep biology delta-wave SWS promotion, sleep homeostasis modulation, sleep efficiency and sleep latency research Sleep EEG research delta-wave induction, SWS vs REM sleep architecture, and sleep stage analysis via polysomnography Sleep neuromodulator pharmacology DSIP vs sedatives and hypnotics

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W., Rook, G

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