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However, REDEFINE 4 (Feb 2026) found CagriSema did not meet noninferiority versus tirzepatide 15 mg at 84 weeks

Interestingly, the NCT02158936 study investigated the efficacy of 5-Aza (75 mg/m 2 subcutaneously once daily for 7 days every 28 days) in combination with the thrombopoietin receptor agonist eltrombopag (50 mg, 100 mg, or 200 mg) as a first-line treatment strategy for MDS patients with thrombocytopenia

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Your doctor will screen for these risks before prescribing the therapy