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The change of brain microenvironment caused by acute cerebral I/R is the main obstacle to nerve function recovery, and a significant reason of stroke recurrence after thrombolytic therapy

Functional variability across liver cell subtypes, immune cells, and metabolic tissues could produce bidirectional or even contradictory effects in different physiological contexts

Physiol Rev (2002) 82:893922

These observations pointed that the use of probiotics could provide additional benefits in heart failure treatment, specifically reducing the severity and improving the prognosis of heart failure post-myocardial infarction

10.1016/j.jinsphys.2012.01.012 J