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Impediments to optimal absorption include a lack of intrinsic factor and inflammatory bowel conditions such as celiac or Crohns disease or irritable bowel syndrome and gut conditions like atrophic gastritis a thinning of the stomach lining

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Dosage Exploration of Combined B-Vitamin Supplementation in Stroke Prevention: A Meta-Analysis and Systematic Review

Vegetarians and vegans are particularly vulnerable, because B12 is derived from animal foods