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Preclinical results indicate that anti-CD19 CAR-T cells are effective in depleting CD19+ B cells in a lupus model, eliminating autoantibody production, reversing disease manifestation in target organs, and increasing lifespan, suggesting long-term efficacy of this therapeutic approach (24, 25)
doi: 10.1007/s40257-017-0298-5 63 ZhaoJDanYLiuZWangQJiangMZhangCet al
doi: 10.1016/j.tplants.2016.09.002 60 MouralT
doi: 10.1111/jhn.12697
C., Wall C., Jameson M
