glutathione supports dna repair synthesis: A two-step pathway. Homeostasis of cellular Glutathione synthesis in the mouse

J Leukoc Biol 81:14341444 Vyas P, Ault K, Jackson CW, Orkin SH, Shivdasani RA (1999) Consequences of GATA-1 deficiency in megakaryocytes and platelets

This hypothesized proteolytic knockdown of components of both the thioredoxin and glutaredoxin systems is consistent with a viral strategy to inhibit DNA synthesis, to increase the pool of ribonucleotides for RNA synthesis, thereby enhancing virion production

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However, preserving final remaining function still valuable for quality of life