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Drug Metab Rev 42:133144

Nevertheless, due to adverse effects of long-term dopamine agonist therapy, an exploration of alternative strategies to medical therapy is warranted, such as surgery

Additionally, when activated, the SAPK/JNK pathway can trigger the P53-YAP1 pathway, decrease GPX4 levels, promote ROS accumulation, and increase susceptibility to ferroptosis [134-136]
The antioxidant moiety of the ubiquinol molecule is attached to the lipophilic triphenylphosphonium cation by a 10-carbon alkyl chain and stabilized for oral administration with the mesylate salt

The WHO recognizes the symptoms as real and potentially severely disabling but has not yet classified EHS as a formal disease entity
