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The effect of tesaglitazar on cardiac function was less substantially in mice with PPAR ablation (Figure 5, E and F) compared with C57BL/6 mice (Figure 1, C and D)

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The bait strain was mated with the Y187 yeast strain (harboring a soybean Mate & Plate Libraries), and the matings were selected on the synthetic medium (SD) without leucine, tryptophan, histidine, and adenine (SD-L/W/H/A) agar plates