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Previous studies showed that unsaturated lipid peroxidation-derived aldehydes such as 4-HNE triggered autophagy in a JNK-dependent manner by activating the endoplasmic reticulum stress (ER) response

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The highest consumption of EDs and the highest sales values of this type of products are observed in the US, Vietnam, Cuba, the UK, Thailand, Mexico, Australia, Germany, Poland, and Saudi Arabia [13]