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It can be associated with: A sudden change in diet A diet with not enough fibre Not drinking enough fluid Loss of 'tone' of the bowel muscles in older people Pregnancy Medicines such as morphine or codeine Having to stay in bed for a long time Lack of exercise Whatever the cause, constipation can be uncomfortable

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"High-Intensity Resistance and Impact Training Improves Bone Mineral Density and Physical Function in Postmenopausal Women With Osteopenia and Osteoporosis: The LIFTMOR Randomized Controlled Trial." Journal of Bone and Mineral Research , vol

So when we eat food, typically, our gut epithelial cells, we have a tight junction thats holding them together