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80 , 81 Lysis of MM cells treated with CD38 mAb is dosedependent and can occur in the presence of bone marrowderived mesenchymal stem/stromal cells, and in patientderived peripheral blood mononuclear cells (PBMCs)

Severe gross brain swelling, volume increase, and intracranial (superior sagittal sinus) hypertension had been counteracted

Common lysosome-targeting groups include 4-(2-hydroxyethyl)morpholine, N,N-dimethylethylenediamine, and diethylene glycol methyl ether, 248 whose weak alkalinity makes them easy to aggregate in the acidic lysosomal environment and thus play a role in targeting lysosomes

Hypoxia-inducible factor-1 is a positive regulator of Sox9 activity in femoral head osteonecrosis