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Mitochondrial dysfunction is another key factor in the decline of macrophage function with aging

The superoxide produced by NOX can increase NF-B transcription, thereby creating another amplifying loop of pro-inflammatory signaling [69]

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Bjrklund G, Chirumbolo S, Geier DA, Kern JK, Geier MR (2017e) Histone deacetylase inhibitors, thimerosal, and autism spectrum disorder

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