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Pignone et al described a decreased serum melatonin and antioxidant enzymes activity in erythrocytes together with proof of increased lipid peroxidation during exacerbations in COPD and asthma [81]

Emerging evidence suggests the existence of a gut-joint axis, wherein the gut microbiome influences the pathogenesis of joint diseases via discrete mechanisms
standardized characterization and robust preclinical models and clinical design will be critical for bringing these promising nanosystems from bench to bedside

Selenium treatment in patients with Graves orbitopathy has been shown to delay disease progression and improve the quality of life
