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Interestingly, a specific GPX1 polymorphism resulting in a proline-to-leucine transition at position 198 (Pro198Leu) is associated with a reduction in GPx1 activity and found to be more prevalent in Keshan patients
[PDF] plos.org Georgiev, Tsvetoslav, and Alexander Krasimirov Angelov
and (c) the olfactory nerve pathway where the drug is taken up into the neurons by endocytotic or pinocytotic mechanisms and transported by intracellular axonal transport to the olfactory bulb [2,16]
10.1038/s41586-021-03510-6 Nature 121 KlemmensenM
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