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Further research is warranted to unravel the new pharmacological mechanisms, toxicity profiles, side effects, and optimal dosages of ferroptosis inhibitors through rigorous preclinical and clinical investigations

[ 412 ] Consistently, another research shows that SETD8 interacts with ELK1 to inhibit the transcription of BACH1, negatively regulating EndMT in diabetic nephropathy (DN), one of the most common complications among diabetic patients, which causes kidney failure

Studies have shown that skin inflammation is not limited to the local area but may trigger systemic inflammatory responses, further leading to the occurrence of other systemic diseases

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