gssg glutathione reductase Pathways OxiSelect Total Glutathione (GSSG/GSH) Assay
Description
doi: 10.1158/1078-0432.CCR-21-0158
Trx becomes reduced through an intermediate selenenylsulfide between Cys-32 of Trx and Sec-498 of TrxR, and Tyr-116 acting by (i) facilitating selenenylsulfide reduction in the reductive half-reaction through resonance effects and, possibly, (ii) facilitating release of the intermediate selenenylsulfide with Trx by its interaction with the selenenylsulfide between Cys-497 and Sec-498
Suppresses appetite via the brains hypothalamic centers
Process Impacts
SteneLCHoneymanMCHoffenbergEJHaasJESokolRJEmeryLet al
