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Often excited state molecules are not kinetically stable in the presence of O 2 or H 2 O and can spontaneously decompose (oxidize or hydrolyze)

& Schulman, E
By contrast, those with the MTHFR A1298C CC genotype (homozygous mutant) tend to have higher folate concentrations without overt clinical symptoms, although vitamin B12 deficiency may be masked (63)

doi: 10.1007/s00204-019-02409-6

Transdermal application of soluble CuII (atsm) increases brain and spinal cord uptake compared to gavage with an insoluble suspension
