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In addition we have also checked hepatic and cardiac mRNA expression of iNOS, eNOS and TNF- (involved in inflammations) and levels of protein expressions of PPAR-, PPAR-, p21, p53, Bcl2, Bax, cleaved caspase 3, cleaved caspase 9 (associated with dyslipidemia, metabolic disturbances, oxidative stress and apoptosis) in this present experimental set up

Long-term safety and efficacy of trifarotene 50 mug/g cream, a first-in-class RAR-gamma selective topical retinoid, in patients with moderate facial and truncal acne

While research on IGF-1 LR3 in humans remains limited, human preclinical data 2 and mechanistic studies offer valuable insight into its biological potential and safety profile

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