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While specific data on micronutrient status during tirzepatide therapy are limited, clinical experience suggests that maintaining optimal nutritional status supports the preservation of lean muscle mass during weight loss, enhances energy levels, and promotes overall treatment tolerability and success

When this vitamin is deficient, the transmission of nerve impulses is impaired

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The peptide has also been associated with normalised NO signaling under both excessive and suppressed NO states, counteracting the implications of NOS blockade and NO overproduction