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Central to these interactions is the gut-thyroid axis, a bidirectional communication pathway that has emerged as a pivotal factor in elucidating the pathogenesis and progression of thyroid diseases (Figure 2)

doi: 10.1016/j.prdoa.2019.07.006, 125

Summary This case demonstrates the potential of TEAM HT, specifically SZRT, to address endocrine therapy-related insomnia in breast cancer patients

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With the increasing importance of exosomes in the TME, future studies should be directed to insightful understanding of the metabolic and lipidomic composition of the exosomes under hypoxic and acidic microenvironment and their contribution to tumor progression