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(2024) 46:e2400495

Because Tesamorelin works by stimulating natural hormonal pathways rather than delivering exogenous growth hormone, it is particularly valuable in research examining feedback mechanisms, receptor sensitivity, and long-term endocrine response patterns
Quinn M, McMillin M, Galindo C, Frampton G, Pae HY, DeMorrow S

There are numerous excellent papers on this topic in the literature (e.g., [33,168,169,170,171,172,173])