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Treatment with N-acetylcysteine (NAC), which boosts cystine/glutamate exchange, corrects cocaine-induced adaptations in NAc glutamatergic transmission and prevents cue- and priming-induced reinstatement of cocaine seeking in an mGlu 2/3 -dependent manner (Moussawi et al., 2009, 2011)

4 DNA methylation mechanisms A conserved family of cytosine methylase enzymes called DNA methyltransferases (DNMTs) catalyze DNA methylation, typically transferring methyl groups from a molecule known as methyl donor S-adenosine methionine (SAM) to a cytosines fifth carbon position

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Synthesis and pharmacological evaluation of noncatechol g protein biased and unbiased dopamine D1 receptor agonists

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