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The idea that GSTs have additional functions not directly derived from their ability to catalyze the formation of GSH conjugates has gained further ground with studies demonstrating that several stress-inducible GSTs protect plants from oxidative injury by functioning as glutathione peroxidases [32,33]

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Nevertheless, emerging trends in nanocarrier design, the advancement of personalised medicine, and integration with therapies (e.g., immunotherapy) underscore the transformative potential of charge-reversible nanocarriers in revolutionising cancer treatment and improving patient outcomes