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42,65,67,7072 Further research has also suggested that TRAF2 plays a key role in facilitating NBDHEX-mediated apoptosis
Excessive accumulation of calcium (Ca2+) is cytotoxic to the heart (162)
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Regarding drug-induced nutritional changes, methotrexate, an inhibitor of folate metabolism, can cause DNA hypomethylation and NTDs [87]
This cell death modality was also proposed as a potential therapeutic target for treating multiple cancers including kidney, ovarian, liver, and pancreatic cancers 3
