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Description
Deamidation of asparagine residues (present in TB-500s Asn in full-length T4, but the fragment contains no asparagine at positions 17-23) accelerates at alkaline pH but is minimized at pH 4-6
This can be due to COMT, MTR or MTRR genetic mutations which help the body convert B12 into its active forms for use at the enzymatic and cellular level

It is important to realize that the MTHFR status does not determine the type of B12 thats best for you, instead its the status and combination of genes like COMT , MTR , MTRR as well as VDR Taq

Sun YY, Xiao Q, Tang W, Chen L, Lin

This makes it easy for researchers to get their questions answered
