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Administration of GH to elderly healthy adults has generally been associated with predictable, albeit modest, effects on body composition and side effects in terms of fluid retention and modest insulin resistance (34)

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The physiological characteristics of the TME are defined by its pH and oxygen tension as well as presence of nutrients, cytokines, chemokines, growth factors, matrix remodeling enzymes, and metabolites [132]

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Cooper A.J.L., Hanigan M.H

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