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Acquired nevi appear during childhood or adulthood
Phelan '90 Mary Pat Phelan '83 Margaret Philbin Ken Phillipp Cathy A
This happens because certain bacteria in the gut break down carnitine into a compound called trimethylamine (TMA)
In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]
