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Increases in proinflammatory cytokine such as TNF, IL-4, IL-6 and IL-13 have all been shown to increase epithelial permeability and have been tied to increased expression of claudin-2 in animal and human models as well as decreased expression of JAM-A and occludin [152, 153]

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Cryogenic transmission electron microscopy: The technique of choice for the characterization of polymeric nanocarriers

Free radicals are formed by the normal processes of the body and are increased with chemical and environmental exposure to toxins

Selenite is more quickly converted than selenate, through the mid-phase of selenide before making SeCys, while selenate needs to be first converted to selenite (54)