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After 6 months on the low carbohydrates diet, serum levels of neurofilament light chain, a biomarker of neuroaxonal damage, were significantly reduced compared with regular diet in patients with relapsing-remitting MS (171)

This central action drastically decreases sympathetic outflow from the central nervous system to the heart, kidneys, and peripheral vasculature (Figure 1)(Patel and Saadabadi, 2025)

The risk of kidney stone formation with long-term use may be reduced by dietary intake of certain foods that induce a mild metabolic alkalosis, which may theoretically increase urine citrate and possibly lower the risk (citrate inhibits crystallization of calcium salt) [145]

Additionally, fluorescently labeled LC3 puncta were visualized using fluorescent imaging analysis

Liang et al., 2024)