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Overall, our fate-mapping in three lung fibrosis models uncover an inward axis of ECM transfer, from PAJs into deep injured lung tissue over days, effectively irrigating lungs with connective tissue that correlates with myofibroblast activation in a temporal and spatial manner (Fig

Trials using adipose- and bone marrow-derived MSCs have reported improvement in pain and disability scores (Orozco et al., 2011

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Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice

0.25mg dose: Draw to 5 units 0.5mg dose: Draw to 10 units 1.0mg dose: Draw to 20 units 1.7mg dose: Draw to 34 units 2.0mg dose: Draw to 40 units 2.4mg dose: Draw to 48 units Total volume in vial: 2mL (200 units)