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Description
n = 3 independent experiments
For instance, although the mitochondrial complex I inhibitor IACS-010759 demonstrated strong anti-leukemia activity in preclinical trials and entered clinical trials, the trials were eventually terminated due to dose-limiting toxicities (DLTS) such as peripheral neuropathy and lactic acidosis
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Local redness or swelling at the injection site
In healthy animals, B-017 did not impact cardiac function in mice (Supplementary Fig
