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Description
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Who Can Benefit

The IMPALA study (a double-blind, randomized, placebo-controlled crossover study with a small sample size over 10 weeks) showed no beneficial effects of ALA compared to placebo, with no significant adverse events (good tolerability) [31]
Future research is necessary to scrutinize cellular and molecular mechanisms of action of AR in cancer cells and the tumour microenvironment, to develop selective modulators of AR activity, and to identify patients with non-prostatic cancer who might benefit from targeting this pathway

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