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Thus, enhanced CYP2E1 did not differentiate bland steatosis from NASH, but could still play a role in disease progression

Meanwhile, HIF-1 was an important protein associated with JNK signaling which was also a key protein in the pathological process of APAP-induced liver injury

GSH is synthesized in every cell of higher eukaryotes, although GSH synthesis and turnover rates, and intracellular concentrations differ among cells and tissues (Hahn et al., 1978

Nineteen-year follow-up of a patient with severe glutathione synthetase deficiency