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Such behavioral deficits in A53T mice were accompanied by the presence of elevated -synuclein monomers and aggregates (Supplemental Figure 1J) and a remarkable loss of dopaminergic neurons in the substantia nigra, as indicated by tyrosine hydroxylase (TH) staining (Figure 1C)

Increasing understanding of the role and regulation of GPX4 will hopefully encourage clinical advancement in cancer therapy, neurodegenerative disorders, and more

Additional benefits include improved blood sugar regulation, enhanced insulin sensitivity, reduced food noise, better metabolic health, and improvements in obesity-related health markers

Radin, L., impraga, M., Vince, S., Kosteli, A

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