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A 2003 study involving epithalamin (the substance from which synthetic epithalon is derived) found that epithalon has a positive effect on cardiovascular, endocrine, immune, and nervous systems, and may prolong the lifespan of elderly human test subjects [10]

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This action may be dependent on increased intracellular Ca 2+ signaling following MET activation

Nat Chem Biol 6 , 507513 (2010)