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The F-box motif is located in the N-terminus of FBL2, followed by 11 leucine-rich repeats (Ilyin et al., 1999) and the CAAX motif, which is thought to be modified by geranylgeranylation (Wang et al., 2005a)

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Dimopoulos MA, Jakubowiak AJ, McCarthy PL, Orlowski RZ , Attal M, Blad J, Goldschmidt H, Weisel KC, Ramasamy K, Zweegman S, Spencer A, Huang JSY, Lu J, Sunami K, Iida S, Chng WJ, Holstein SA, Rocci A, Skacel T, Labotka R, Palumbo A, Anderson KC

These findings underscore the complexity of COVID-19's effects on the nervous system and its long-term consequences

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