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Engineering xylose utilization in Yarrowia lipolytica by understanding its cryptic xylose pathway

Tang W, Zhang L, Zheng Y, Pan L, Niu T

8-hydroxyguanine (8-OHG) activates the cGAS-STING-IRF3 axis, which significantly increases IFN- secretion and promotes M1 polarization

In hypertensive vascular remodeling, mechanical overload activates the Piezo1 channel, inducing mitochondrial Ca 2+ overload and DRP1-dependent fission, leading to VSMC hyperplasia