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Description
Vitamin B12 does require the initial loading dose period, especially in very deficient cats, so improvements will not be immediate
EMBO J 42:e112559
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Because vitamin B12 works with almost every other vitamin and mineral directly and indirectly getting it working for you is vital in the proper treatment of MTHFR.
Short answer: It appears tolerable in very limited early human data, but there is not enough evidence to call it safe for general use
