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doi: 10.1097/MCG.0000000000000498
In a clinical study of AD patients, alpha-lipoic acid slowed cognitive decline [234]

The suspension was centrifuged (1,000 g , 2 min, r.t.), and the supernatant was removed
These studies suggest that B12 supplementation could be explored in scenarios where increased methylation potential is required, analogous to the FA supplementation of pregnant women to prevent NTDs
